Hargreave

Determining asthma treatment by monitoring sputum cell counts: cost comparison with clinical monitoring.  Can Respir J

Inman

Comparison between conventional and clinical assessment of experimental lung fibrosis. Translational Medicine 2008 6:16 *

Janssen

Contractility of renal glomerulus and mesangial cells: lingering doubts and strategies for the future.  Medical Hypotheses and Research 4:1-9, 2008

Janssen

Critical issues related to real-time fluorescence imaging of renal tissues using confocal microscopy.  Kidney International 73:656, 2008

Janssen

Ginger attenuates acetylcholine-induced contraction and Ca2+ signalling in murine airway smooth muscle cells.  Canadian Journal of Physiology and Pharmacology

Janssen

Isoprostanes constrict human radial artery through stimulation of thromboxane-receptors, Ca2+-release and RhoA activation.  Journal of Cardiovascular Thoracic Surgery 135(1):131-8, 2008

Janssen

Isoprostanes may mediate vasospasm in human radial artery following coronary artery by-pass surgery.  Proceedings of the 7th International Congress on Coronary Artery Disease.

Janssen

Ryanodine receptors decant internal Ca2+  store  in human and bovine airway smooth muscle.  European Respiratory Journal

Janssen

Studying channel and receptor physiology in podocytes.  Letter to the Editor.  Kidney International 73:364, 2008

Kolb

Animal Models of Pulmonary Fibrosis: How Far from Effective Reality? Am J Physiol Lung Cell Mol Physiol 2008; 294: L151

Kolb

Comparison between conventional and "clinical" assessment of experimental lung fibrosis. J Transl Med 2008

Kolb

Progressive pulmonary fibrosis is mediated by TGF-  isoform 1 but not TGF- 3. Int J Biochem Cell Biol 2008; 40:484-495

Kolb

TGF-beta receptor II in Epithelia Versus Mesenchyme Plays Distinct Role in Developing Lung. Eur Respir J 2008

Kolb

The bleomycin model: a useful tool to investigate therapies for IPF? Int J Biochem Cell Biol 2008; 40: 362-382

Kolb

Comparison between conventional and clinical assessment of experimental lung fibrosis. Translational Medicine 2008 6:16 *

Labiris

Comparison between conventional and clinical assessment of experimental lung fibrosis. Translational Medicine 2008

McIvor RA

Canadian  Adult  Asthma  Update  2008  Key Recommendations:   A Focus on Translating Knowledge into Action in Primary Care Can Respir J 2008: Editorial In Press April 2008

McIvor RA

Coccidioides immitis: A case of misidentified mycosis Can Resp J In Press Accepted Feb 2008

McIvor RA

Tobacco control and nicotine addiction. Ontario Thoracic Reviews Winter 2008; 20: (1) : 1-6

Nair

Determining asthma treatment by monitoring sputum cell counts: cost comparison with clinical monitoring.  Can Respir J 2008 (in press)

Nair

Effects of leptin on airway smooth muscle biology. Am J Respir Cell Mol Biol 2008. epub

Nair

Managing asthma by monitoring sputum neutrophil count. Chest 2008 (in press)

O'Byrne PM

 Antisense oligonucleotides against CCR3 and the common beta chain attenuate allergen-induced responses in mild allergic asthmatics   Am J Respir Crti Care Med: in press.

O'Byrne PM

Global strategy for asthma management and prevention: GINA executive summary.  Eur Respir J 2008; 31:143-78.

O'Byrne PM

Sputum eosinophils and the response of exercise-induced bronchoconstriction to inhaled corticosteroids in asthma.  Chest 2008;133:404-11.

O'Byrne PM

START Study 5-Year Follow-up: Effectiveness of early intervention with budesonide in mild persistent asthma.  J Allergy Clin Immunol 2008 (in press).

O'Byrne PM

Sustained maintenance therapy in asthmatic patients not on inhaled corticosteroids: combined therapy with salmeterol and fluticasone or fluticasone alone.  Respir Med: 2008; 102:77-81.

O'Byrne PM

The effect of IVX-0142, a heparin-derived hypersulfated disaccharide, on the allergic airway responses in asthma.  Allergy (in press - 2008).

Sears MR

Budesonide/formoterol maintenance and reliever therapy:  Impact on inflammation in asthma.  Eur Respir J 2008; In Press

Sears MR

Cigarette smoking and allergic sensitization:  a 32-year population-based cohort study.  J Allergy Clin Immunol 2008;121:38-42

Sears MR

How should we construct psychiatric family history scores?  A comparison of alternative approaches from the   Dunedin Family Health History Study.   Psychological Medicine 2008

Sears MR

Links between anxiety and allergies:  Psychobiological reality or possible methodological bias?  J Personality 2008;

Sears MR

Long-acting bronchodilators in COPD.  Chest 2008;133:

Allen

Changing pattern of sputum cell counts in successive exacerbations of airway diseases. Respir Med 2007; 101: 2217 20.

Allen

The effect of obesity on airway inflammation -  a cross sectional analysis of body mass index and sputum cell counts. Clin Exp Allergy 2007; 37: 1049 54

Allen

Sputum neutrophilia masks eosinophilic bronchitis during exacerbations. Can Respir J 2007; 14: 281 4.

Cox

Liver X receptor stimulates cholesterol efflux and inhibits expression of pro-inflammatory mediators in human airway smooth muscle cells. Mol Endocrin 2007

Cox

Modulation of human airway smooth muschle migration by lipid mediators and Th-2 cytokines.  Am J Respir Cell Mol Biol 2007; 37:240-247.

Cox

Persistent benefit of bronchial thermoplasty in asthma at one year. N Engl J Med 2007; 356:1327-1337

Cox

Tiotropium in Combination with Placebo, Salmeterol, or Fluticasone-Salmeterol for Treatment of Chronic Obstructive Pulmonary Disease: A Randomized Trial. Ann Intern Med. 2007

Dolovich

Positron Emission Tomography versus Positron Emission Tomography – Computed Tomography: Tools for Imaging the Lung. Proc Amer Thoracic Soc 2007; 4(4): 328-333

Hargreave

Changing types of bronchitis during successive exacerbations of airway disease. Respir Med 2007; 101: 2217-20

Hargreave

Cost-effectiveness of various diagnostic approaches for occupational asthma.  Can Respir J 2007; 14: 276-80

Hargreave

Effect of obesity on airway inflammation: a cross-sectional analysis of body mass index and sputum cell counts.  Clin Exp Allergy 2007; 37:1049-54

Hargreave

Effects of montelukast compared to double dose budesonide on airway inflammation and asthma control.  Resp Med 2007; 101: 1652-8.

Hargreave

Evolution of Canadian Asthma Guidelines.  Can Med J 2007

Hargreave

Quantitative sputum cell counts as a marker of airway inflammation in clinical practice.  Curr Opin Allergy Clin Immunol 2007; 102-6

Hargreave

Sputum neutrophils masks eosinophilic bronchitis during exacerbations.  Can Respir J 2007; 14: 218-4 

Hargreave

The efficiency of sputum cell counts in cystic fibrosis.  Can Respir J 2007; 14: 99-103

Hargreave

Understanding allergic asthma from allergen inhalation tests. Can Respir J 2007; 14: 414-8

Inman

A GABAergic system in airway epithelium is essential for mucus overproduction in asthma. Nat.Med. 13:862-867. 2007

Inman

Components of airway hyperresponsiveness and their associations with inflammation and remodeling in mice. J.Allergy Clin.Immunol. 119:848-854. 2007

Inman

Oral treatment with live Lactobacillus reuteri inhibits the allergic airway response in mice. Am.J.Respir.Crit Care Med. 175:561-569. 2007

Inman

Sputum Eosinophils and the Response of Exercise-Induced Bronchoconstriction to Corticosteroid in Asthma. Chest 2007

Inman

The effects of allergen on airway narrowing dynamics as assessed by a lung slice technique. European Resp J 2007

Inman

Three-dimensional CT Imaging in an animal model of emphysema. Eur Respir J 2007; 30; 1082-89

Janssen

Airway smooth muscle dynamics: a final common pathway of airway obstruction in asthma.  European Respiratory Journal 29:834-860, 2007

Janssen

E-ring isoprostane augments cholinergic neurotransmission in bovine trachealis via FP-subtype prostanoid receptors.  American Journal of Respiratory Cell and Molecular Biology 37:739-747, 2007

Janssen

E-ring isoprostanes stimulate a Cl- conductance in bovine airway epithelium via EP prostanoid receptors coupled to cyclic nucleotides.  American Journal of Respiratory Cellular and Molecular Biology 38:88-94, 2007

Janssen

Invited review: Ionic mechanisms in airway smooth muscle.  European Respiratory Journal 30:114-133, 2007

Janssen

Kinetics of in vitro bronchoconstriction in an elastolytic mouse model of emphysema.  European Respiratory Journal  30(4):691-700, 2007

Janssen

Modulation of human airway smooth muscle migration by lipid mediators and Th-2 cytokines.  American Journal of Respiratory and Cell Molecular Biology 37:240-247, 2007

Janssen

Pharmacological actions of isoprostane metabolites and phytoprostanes in human and bovine pulmonary smooth muscles.  Prostaglandins Leukotrienes and Essential Fatty Acids 76(1):57-64, 2007

Janssen

ROCs and SOCs: What’s in a name?  Cell Calcium 41:245-247, 2007

Janssen

Sodium and asthma: something borrowed, something new. American Journal of Physiology 293:L1369-L1373, 2007

Janssen

State of clinical research ethics in Pakistan.  Letter to the Editor.  Nature Medicine 13:1011, 2007

Janssen

Store-refilling involves both L-type calcium channels and reverse-mode sodium calcium exchange in airway smooth muscle.  European Respiratory Journal 30:269-278, 2007

Janssen

The reverse-mode of the sodium-calcium exchanger provides a source of calcium for store-refilling following agonist-induced calcium mobilization.  American Journal of Physiology 292:L438-L447, 2007

Janssen

U46619-induced tyrosine phosphorylation and modulation by genistein, daidzein and equol.  Journal of Cardiovascular Pharmacology 50:441-448, 2007

Johnston NW

Attenuation of the September epidemic of asthma exacerbations in children:  A randomized controlled trial of montelukast added to usual therapy. Pediatrics. 2007 Sep;120(3):e702-12.

Johnston NW

The Similarities and Differences of Epidemic Cycles of COPD and Asthma Exacerbations.  Proceedings of the American Thoracic Society 2007;4:591-596

Kolb

Gene therapy for cystic fibrosis.  Multidiscipl Resp Med 2007; 1: 72-77.

Kolb

TGFbeta, Smad3 and the process of progressive fibrosis. Biochem Soc Trans 2007; 35: 661-664

Kolb

Three-dimensional CT Imaging in an animal model of emphysema. Eur Respir J 2007; 30; 1082-89

Kolb

Transforming growth factor-beta1 induces progressive pleural scarring and subpleural fibrosis. J Immunol 2007; 179: 6043-51

Labiris

Efficiency of Sputum Processing for Inflammatory Indices in Cystic Fibrosis. Canadian Respiratory Journal 2007 14(2):99-103.

Labiris

Justifying the number of animals for each experiment. Nuclear Medicine and Biology 2007 34:229-32

Labiris

Randomized Trial of Influences on Patient Preferences for Anticoagulant Drug Therapy: What’s in a Name? Canadian Medical Association Journal 2007 176(11):1583-7

Labiris

Three Dimensional computered tomography imaging in an animal model of emphysema. Eur Respir J 2007 30(6):1082-9.

Larché M.

 Allergen-specific immunotherapy. Nature Reviews Immunology (2006) 6 761-771.

Larché M.

Airway expression of calcitonin gene-related peptide in T cell peptide-induced late asthmatic reactions. Allergy 2007;62:495-503. IF 5.33

Larché M.

Indirect allorecognition of HLA public T cell epitopes: implications for the mechanisms of graft rejection and acceptance. Am J Transplantation 2007;7:1148-57. IF 6.84

Larché M.

Late asthmatic reactions provoked by inhalation of allergen-derived T cell peptide epitopes are associated with increased airway hyperresponsiveness and accumulation of CD3+, CD4+ and TARC+ cells in the airways. Thorax 2007;62:749-56. IF 6.06

Larché M.

Peptide immunotherapy for allergic diseases. Allergy (2007) 62(3):325-31. IF 5.33

Larché M.

Peptide immunotherapy in allergic asthma generates immunological tolerance associated with linked-epitope suppression. J. Exp. Med. 2007 IF 14.48

Larché M.

Regulatory T cells in allergy and asthma. Chest (2007) 132(3):1007-14. IF 3.92

Larché M.

Regulatory T celss in Allergy and Asthma. Timely Topics in Medicine; Respiratory Disease. Prous Sciences (2007)

Larché M.

Update on the current status of peptide immunotherapy. J Allergy Clin Immunol. 2007;119:906-9. IF 8.83

McIvor RA

 Do Long Acting Beta Agonists increase the risk of severe respiratory events in asthma patients? Can Fam Physician April 2007: (53): 687-8

McIvor RA

A one year randomized controlled trial of roflumilast in treatment of COPD. Am. J. Respir. Crit. Care Med.  2007 Jul 15;176(2):154-61; E-published ahead of print on April 26, 2007 as doi:10.1164/rccm.200610-1563OC.

McIvor RA

An approach to chronic obstructive pulmonary disease in primary care. Can Fam Physician In Press Accepted Oct 1st 2007

McIvor RA

Canadian  Adult Asthma Guidelines Update Ontario Respiratory Care Society (ORCS) Update Fall 2007; 23 (3): 1-6

McIvor RA

Canadian economic evaluation of Budesonide/Formotorol as maintenance and reliever treatment in patients with moderate to severe asthma. Can Respir  Journal 2007;14 (5): 269-275

McIvor RA

Chronic Obstructive Pulmonary Disease in the Older Adult: New Approaches to an Old Disease Geriatrics & Aging 2007; 10 (4): 213-220

McIvor RA

Chronic Obstructive Pulmonary Disease: Improving health outcomes and quality management Ontario Thoracic Reviews Winter 2007; 1-6

McIvor RA

Future Options for Disease Intervention: Important Advances in Phosphodiesterase (PDE) 4 Inhibitors Eur Respir Rev 2007; 16: 105, 105-112

McIvor RA

Genetics of asthma and chronic obstructive pulmonary disease ( Book Review ) Resp Care Sept 2007:52(9): 2-3

McIvor RA

Little P10 minute consultation: Chronic Obstructive Pulmonary Disease BMJ  2007; 334:798.

McIvor RA

Respiratory guidelines implementation in Canada Can Respir J 2007:14(6) 329-330 Editoria

McIvor RA

The reality of asthma control study: a call to action for Canadian family physicians. Can Fam Physician April  2007: (53): 672-677

McIvor RA

Tiotropium in Combination with Placebo, Salmeterol, or Fluticasone-Salmeterol for Treatment of Chronic Obstructive Pulmonary Disease: A Randomized Trial. Ann Intern Med. 2007; 146: 545-555

Nair

Addition of long acting bronchodilators to inhaled corticosteroids in the treatment of COPD. Pol Arch Med Wewn 2007; 117: 6 8.

Nair

Changing pattern of sputum cell counts in successive exacerbations of airway diseases. Respir Med 2007; 101: 2217 20.

Nair

Expression and function of liver X receptors in human airway smooth muscle cells. Mol Endocrinol 2007; 21: 1324 34

Nair

Modulation of human airway smooth muscle migration by lipid mediators and Th 2 cytokines. Am J Respir Cell Mol Biol 2007; 37: 240 7.

Nair

Sputum neutrophilia masks eosinophilic bronchitis during exacerbations. Can Respir J 2007; 14: 281 4.

Nair

The effect of obesity on airway inflammation -  a cross sectional analysis of body mass index and sputum cell counts. Clin Exp Allergy 2007; 37: 1049 54

Nair

Ventilation and perfusion lung scintigraphy of allergen induced airway responses in atopic asthmatic subjects.  Can Respir J 2007; 14: 285 91

O'Byrne PM

 An Essential Role for a Novel Airway Epithelial GABAergic System in Mucus Overproduction in Allergic Asthma.  Nature Med 2007; 13:862-7.

O'Byrne PM

Acute asthma interventions: insights from the STAY study.  J Allergy Clin Immunol 2007; 119:1332-6.

O'Byrne PM

Circulating myeloid and plasmacytoid dendritic cells after allergen inhalation in asthmatic subjects.  Allergy 2007; 62:1139-45.

O'Byrne PM

Combining LABA and ICS in patients with severe COPD.  Pol Arch Med Wewn. 2007;117:6-8.

O'Byrne PM

GINA guidelines on asthma and beyond.  Allergy. 2007; 62:102-112.

O'Byrne PM

How much is too much?  The treatment of mild persistent asthma.  Eur Respir J 2007; 30:403-6.

O'Byrne PM

The allergen bronchoprovocation model.  An important tool for the investigation of new asthma anti-inflammatory therapies.  Allergy 2007; 62:1101-10

O'Byrne PM

The demise of anti-IL-5 as treatment for asthma, or not.  Am J Respir Crit Care Med 2007; 176:1059-60.

O'Byrne PM

The effects of inhaled Budesonide and Formoterol, alone and together, on airway responses when given after allergen challenge.  J Allergy Clin Immunol 2007; 119:322-327.

O'Byrne PM

Understanding allergic asthma from allergen inhalation tests.  Can Respir J 2007; 14:414-8.

Sears MR

 Adiposity, asthma and airway inflammation.  J Allergy Clin Immunol  2007; 119:634-9

Sears MR

 Interactions between breast-feeding, specific parental atopy, and sex on development of asthma and atopy. J Allergy Clin Immunol 2007; 119:1359-66

Sears MR

Adiposity, asthma, and airway inflammation.  J Allergy Clin Immunol 2007;119:634-639

Sears MR

Airflow obstruction in young adults in Canada.  Can Respir J  2007; 14:221-7

Sears MR

Association between exhaled nitric oxide and systemic inflammatory markers.  Ann Allergy Asthma Immunol 2007;99:534-539

Sears MR

Asthma mortality in southern Brazil:  is there a changing trend?  J Asthma 2007; 44:133-6

Sears MR

Attenuation of the September epidemic of asthma exacerbations in children: a randomized controlled trial of montelukast added to usual therapy. Pediatrics  2007;120:e702-712

Sears MR

Canadian economic evaluation of budesonide/formoterol as maintenance and reliever treatment in patients with moderate to severe  asthma.  Can Respir J 2007;14:269-75

Sears MR

Factors affecting exhaled nitric oxide measurements:  the importance of sex.  Respir Research 2007;8:82

Sears MR

Lung function decline in asthma.  Eur Respir J. 2007;30:411-413

Sears MR

Mapping health on the Internet: A new tool for environmental justice and public health research.  Health Place 2007; 13:72-86

Sears MR

Prediction of differential adult health burden by conduct problem sub type in males.  Arch Gen Psychiatry 2007; 64:476-84

Sears MR

Systemic inflammation and lung function in young adults.  Thorax 2007;62:1064-1068

Sears MR

Understanding the September asthma epidemic. J Allergy Clin Immunol 2007;120:526-529

Sehmi

Cord blood hemopoietic progenitor profiles predict acute respiratory symptoms in infancy. Paediatric Allergy and Immunology 2007

Todd

An approach to chronic obstructive pulmonary disease in primary care. Can Fam Physician 2007 (accepted)

Todd

The effect of obesity on airway inflammation - a cross-sectional analysis of body mass index and sputum cell counts. Clin Exp Allergy 2007;37:1049-1054

Allen

Does laparoscopic Nissen fundoplication lead to chronic gastrointestinal dysfunction? Surgical Endoscopy and other Interventional Techniques   Volume: 20    Issue: 9    Pages: 1360-1363    Published: SEP 2006

Allen

Effect of pregnancy on effectiveness of laparoscopic Nissen fundoplication. Surgical Endoscopy and other Interventional Techniques    Volume: 20    Issue: 3    Pages: 385-388    Published: MAR 2006 

Allen

Surgical outcome in gastro-esophageal reflux disease patients with inadequate response to proton pump inhibitors. Surgical Endoscopy and other Interventional Techniques    Volume: 17    Issue: 7    Pages: 1029-1035    Published: JUL 2003

Cox

A prospective feasibility study of bronchial thermoplasty in the human airway. Chest 2005;127:1999-2006.

Cox

A randomized clinical trial of lung volume reduction surgery versus best medical care for patients with advanced emphysema; a two-year study from Canada.  Annals of Thoracic Surgery 2006; 81:34-321.

Cox

Bronchial thermoplasty for asthma. Am J Respir Crit Care Med 2006; 173: 965-969.

Cox

Cell specific gene expression in patients with usual interstitial pneumonia.  Am J Resp Crit Care Med 2006; 1;174(5):557-65

Dolovich

 Synthesis and in Vitro Evaluation of (18)F- and (19)F-Labeled Insulin: A New Radiotracer for PET-based Molecular Imaging Studies. J Med Chem. 2006 Feb 23;49(4):1466-1474.

Dolovich

Anti-inflammatory effects of once daily low dose inhaled ciclesonide in mild to moderate asthmatic patients. Allergy 2006;61(5):537-42

Hargreave

Eosinophilic bronchitis in asthma:  a model for establishing dose-response and relative potency of inhaled corticosteroids.  J Allergy  Clin Immol 2005; 117: 989-94

Hargreave

Asthma, COPD and bronchitis are just componets of airway disease. Eur Respir J 2006; 28: 264-267

Hargreave

Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations.  Eur Resp J 2006; 27: 483-94.

Hargreave

Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest 2006; 129(1 Suppl):1S-23S.

Hargreave

Predictors of loss of asthma control induced by corticosteroid withdrawal.  Can Resp J 2006; 13:129-33

Hargreave

Stable COPD: predicting benefit from high-dose corticosteroid treatment. Eur Respir J 2006; 27: 964-71

Hargreave

The clinical utility of quantitative sputum cell counts to measure airway inflammation.  The Lung Association.  Research Review 2006; 3:8-9.

Inman

Effect of  dose and duration of therapy on exercise-induced brochoconstriction in patients with asthma. J.Allergy Clinical.Immunology. 117:1008-1013. 2006

Inman

Exposure Attenuates Airway Hyperresponsiveness and T Call Function in Mice. Int.Arch.Allergy Immunol. 141:130-140. 2006

Inman

Regional defferences in the pattern of airway remodeling following chronic alergen exposure in mice. Respir.Res. 7:120. 2006

Inman

Sample size calculations and methacholine challenge tests. In.J.Clin.Pharmacol.Ther. 44:449-450. 2006

Janssen

Invited review: New therapies for asthma.  Respiratory Research 7:123, 2006

Janssen

Isoprostane-induced airway hyperresponsiveness is dependent upon Rho/ROCK signaling and internal Ca2+-handling.  American Journal of Physiology 291:1177-1184, 2006

Janssen

Membrane potassium currents in human radial artery and their regulation by nitric oxide donor.  Cardiovascular Research 71:383-392, 2006

Janssen

Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and relaxant stimuli.  European Respiratory Journal 28:703-711, 2006

Johnston NW

The epidemiology of asthma exacerbations.  Thorax, 2006;61:722-728. (5)

Johnston NW

The September epidemic of asthma exacerbations: School children as disease vectors.  J Allergy Clin Immunol 2006;117:557-62 (17)

Kolb

Gene therapy for pulmonary disease. Chest 2006; 130: 879-884.

Kolb

Models of pulmonary fibrosis. Drug Discovery Today: Disease Models 2006, 3:243-249

Kolb

Smad3 Signaling involved in Pulmonary Fibrosis and Emphysema. Proc Am Thor Soc 2006; 3: 696-702

Kolb

Strategies targeting fibrosis in pulmonary disease. Drug Discovery Today: Therapeutic Strategies 2006; 3: 99-103;

Kolb

Targeting genes for treatment in idiopathic pulmonary fibrosis. Proc Am Thor Soc 2006; 3: 389-393

Kolb

The transforming Growth Factor-beta (TGF-b) family and pulmonary fibrosis. Drug Discovery Today: Disease Mechanisms 2006; 3: 99-103;

Labiris

Synthesis and In Vitro Evaluation of 18F and 19F-Labeled Insulin: A New Radiotracer for PET-based Molecular Imaging Studies Journal of  Medicinal Chemistry 2006 49: 1466-1474

Labiris

Systematic Overview of Drug Interactions with Antidepressant Medications.  Can J Psychiatry 2006;51:300-316

Larché M.

 Analytical validation of a novel flow cytometric-based IgE-Facilitated Allergen Binding (FAB) assay as a tool for monitoring grass pollen immunotherapy. J Immunol Methods (2006) 317 71-79 IF 2.40

Larché M.

Phospholipase A2 peptide immunotherapy reduces late-phase skin allergen responses and is associated with increased IL-10 production and Socs3 gene expression in blood leukocytes. Clin. Exp. Allergy (2006) 36 465-474. IF 3.67

McIvor RA

Asthma control in Canada remains suboptimal: the Reality of Asthma Control (TRAC) study.Can Respir J. 2006 Jul-Aug;13 (5):253-9

McIvor RA

Canadian Asthma Guideline Group.  Safety and effectiveness of long-acting inhaled beta-agonist bronchodilators when taken with inhaled corticosteroids. Ann Intern Med. 2006 Nov 7;145 (9):692-4. Review.

McIvor RA

Dissemination and implementation of asthma guidelines in Canada. Can Respir J 2006: 13: Suppl A 24A-25A

McIvor RA

Dissemination and implementation of guidelines on asthma and COPD in Canada: Where do we go from here? Can Respir J 2006: 13: Suppl A 41A-42A

McIvor RA

Implementing practice guidelines: A workshop on guideline dissemination and implementation with a focus on asthma and COPD. Can Respir J 2006: 13: Suppl A 1A-4A

McIvor RA

Management of chronic asthma in diverse regions of the world. IUTLD May 2006: 10 (5):1-10

McIvor RA

Quality of life outcome measures in COPD: Integration into clinical practice. Pulmonary Reviews 2006 Sept ; 1-5

McIvor RA

The role of omalizumab in the treatment of severe allergic asthma. Can Respir J. 2006 Jul-Aug;13 Suppl B:1B-9B.

Nair

Altered respiratory physiology in obesity. Can Respir J 2006; 13: 203 10

Nair

Effects of salmeterol and fluticasone on allergen provoked changes in nasal electrical potential and nasal inflammation. Allergy 2006; 61: 731 6.

Nair

Eosinophilic bronchitis in asthma: a model for establishing dose response and relative potency of inhaled corticosteroids.  J Allergy Clin Immunol 2006; 117: 989 94.

Nair

Monitoring asthma treatment using sputum cell counts: effects on exacerbations. Eur Respir J 2006; 27: 483 94

Nair

Pharmacological management of mild or moderate persistent asthma. Lancet 2006; 368: 794 803

Nair

Predictors of asthma exacerbation induced by steroid withdrawal. Can Respir J 2006; 13: 129 33

Nair

Role of extracellular matrix and its regulators in human airway smooth muscle biology. Cell Biochem Biophys 2006; 44: 139 46.

Nair

Treatment strategy for asthma: all for one and one for all? Chest 2006; 129: 221 3.

Nair

Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations.  Eur Resp J 2006; 27: 483-94.

O'Byrne PM

 Effectiveness of early budesonide intervention in white versus asian patients with asthma: 3-year results of the START study.  Respirology: 2006:11; 767-775.

O'Byrne PM

An assessment of the anti-inflammatory properties of low dose ciclesonide in asthmatic patients.  Allergy 2006: 61:537-42.

O'Byrne PM

Asthma Management Guidelines: the issue of implementation.  Prim Care Respir J 2006;15:5-6.

O'Byrne PM

Cytokines or their antagonists for the treatment of asthma.  Chest 2006; 130:244-50.

O'Byrne PM

Early intervention of recent onset mild persistent asthma in children aged under 11 years: the steroid treatment as regular therapy in early asthma (START) Trial. Pediatric Allergy and Immunology. 2006; 17:7-13.

O'Byrne PM

Effect of dose and duration of therapy on exercise-induced bronchoconstriction in patients with asthma J Allergy Clin Immunol  2006: 117:1008-13.

O'Byrne PM

Effects of Inhaled ciclesonide on circulating Th1/Th2 cells in atopic asthmatics after allergen challenge.  Clin Exp Allergy 2006; 36:1417-24.

O'Byrne PM

Effects of intranasal fluticasone and salmeterol on allergen-induced nasal responses.  Allergy:  2006; 61:731-6.

O'Byrne PM

Immunostimulatory sequences regulate interferon-inducible genes but not allergic airway responses.  Am J Respir Crit Care Med 2006; 174:15-20.

O'Byrne PM

Montelukast treatment attenuates the increase in myofibroblasts following low dose allergen challenge.  Chest 2006; 130:741-53.

O'Byrne PM

Predictors of loss of asthma control induced by corticosteroid withdrawal. Can Respir J. 2006; 13:129-33.

O'Byrne PM

The effects of early intervention with inhaled budesonide on lung function in mild persistent asthma.  Chest 2006: 129:1478-85.

O'Byrne PM

The pharmacological management of mild and moderate persistent asthma.  Lancet 2006: 368;794-803.

O'Byrne PM

β2 déjà vu.  Chest 2006: 129 :3-5

Sears MR

 Associations between respiratory symptoms, lung function and gastro-oesophageal reflux symptoms in a population-based birth cohort.  Respir Research 2006;7:142;1-9

Sears MR

 Asthma Exacerbations I: Epidemiology.  Thorax 2006;61:722-728.

Sears MR

Seasonal patterns of asthma exacerbations. In: Johnston SL and O’Byrne P, eds.  Exacerbations of Asthma.  Taylor and Francis, London UK.  October 2006, 57-76

Sears MR

Severe chronic asthma.  Ped Respir Reviews 2006;75:S123-S124.

Sears MR

The Ontario Asthma Regional Variation Study:  emergency department visit rates and the relation to hospitalization rates.  Chest 2006;129:909-917.

Sears MR

The September epidemic of asthma hospitalization:  school children as disease vectors.  J Allergy Clin Immunol 2006;117:557-562.

Todd

Altered respiratory physiology in obesity. Can Respir J 2006;13:203-210

Cox

Lung volume reduction surgery vs medical treatment for patients with advanced emphysema.  Chest 2005;127:1166-1177

Dolovich

Pediatric Asthma, Allergy & Immunology

Dolovich

Device Selection and Outcomes of Aerosol Therapy: ACCP Evidence-Based Guidelines. CHEST 2005;127: 335-371.

Dolovich

In Vitro Estimations of In Vivo Jet Nebulizer Efficiency Using Actual and Simulated Tidal Breathing Patterns.  J Aerosol Med 2005 18(4):427-38

Hargreave

Failure of montelukast to reduce sputum eosinophilia in high dose corticosteroid-dependent asthma.   Eur Respir J 2005; 25: 41-6

Hargreave

Steroid naïve eosinophilic asthma: anti-inflammatory effects of fluticasone and montelukast. Thorax 2005; 60: 100 – 5

Inman

Epithelial expression of profibrotic mediators in a model of allergen-induced airway remodeling. Am.J.Respir.Cell Mol.Biol. 32:99-107. 2005

Inman

Haemopoietic mechanisms in murine allergic upper and lower airway inflammation. Immunology 114:386-396. 2005

Inman

House dust mite facilitates ovalbumin-specific allergic sensitization and airway inflammation.  Am.J.Respir.Crit Care Med. 172:314-321. 2005

Inman

Increased eosinophil-lineage committed progenitor cells in the lungs of allergen challenged mice: A time course study.  J Allergy Clin Immunol.

Janssen

8-isoPGE2 activates Ca2+-dependent K+ current via cAMP signaling pathway in murine renal artery.  European Journal of Pharmacology 520:22-28, 2005

Janssen

Airway smooth muscle excitation-contraction coupling and airway hyperresponsiveness.  Canadian Journal of Pharmacology and Physiology 83:725-732, 2005

Janssen

Alteration of arterial smooth muscle potassium channel composition and BK(Ca) current modulation in hypertension.  European Journal of Pharmacology 514:111-119, 2005

Janssen

Atherosclerosis of radial arterial graft may increase the potential of vessel spasm in coronary bypass surgery.  Journal of Thoracic and Cardiovascular Surgery 130:1477-1478, 2005

Janssen

Cyclopiazonic acid activates a Ca2+-permeable, non-selective cation conductance in porcine and bovine tracheal smooth muscle.  Journal of Applied Physiology 99:1759-1768, 2005

Janssen

E-ring isoprostanes evoke chloride current in bovine bronchial epithelium.  Medical Hypotheses and Research 2:573-579, 2005

Janssen

Intracellular Cl— fluxes play a novel role in Ca2+-handling in airway smooth muscle.  American Journal of Physiology 290(6):L1146-53

Janssen

Isoprostanes: not just markers, but also catalysts of Alzheimer’s Disease?  Medical Hypotheses and Research 2:525-532, 2005

Janssen

Regulation of Rho/ROCK signaling in airway smooth muscle by membrane potential and [Ca2+]i.  American Journal of Physiology 289:L574-L582, 2005

Janssen

The pulmonary biology of isoprostanes.  Antioxidants and Redox Signaling 7:244-255, 2005

Johnston NW

The September epidemic of asthma exacerbations in children: A search for etiology.  J. Allergy Clin Immunol 2005; 112:132-138 (34)

Kolb

Idiopathic Pulmonary Fibrosis: is there light at the end of the tunnel? Ont Thor Rev 2005; 18: 1-6

Kolb

Progressive TGF  Induced Lung Fibrosis Is Blocked By An Orally Active ALK5 Kinase Inhibitor. Am J Respir Crit Care Med 2005; 171:889-898

Kolb

TGFbeta and Smad3 signalling link inflammation to chronic fibrogenesis.  J Immunol 2005; 175:5392-5395

Kolb

Transforming growth factor-b peptide signaling in lung development, bronchopulmonary dysplasia, lung fibrosis and emphysema. Curr Resp Med Rev 2005; 1:325-329

Kolb

Transforming growth factor-beta: importance in long-term peritoneal membrane changes. Perit Dial Int. 2005 Feb;25 Suppl 3:S15-7.

Labiris

Imaging Drug Delivery and Drug Responses in the Lung. Proc Am Thorac Soc 2005 1:329-337

Labiris

Systematic Overview of Warfarin and Its Drug and Food Interactions. Arch Intern Med 2005 165:1095-1106

Larché M.

EAACI CME Accreditation Committee. Continuing medical education: an international reality. Allergy. 2005 60 739-42. IF 5.33

Larché M.

Evidence for recruitment of activated Th1 cells (CD4+ CD25+; CD4+ IFNg+) in allergen-challenged skin sites of atopic subjects following T cell peptide therapy. Clin. Exp. Allergy (2005) 35 52-58. IF 3.67

Larché M.

Peptide therapy for allergic diseases: basic mechanisms and new clinical approaches. Pharmacology and Therapeutics (2005) 108 353-361. IF 7.5

Larché M.

Peptide-based immunotherapy: A novel strategy for allergic disease. Expert Reviews of Vaccines (2005) 4 883-891.

Larché M.

Peptide-based therapeutic vaccines for allergic and autoimmune diseases. Nature Medicine (2005) 11 S69-76.

Larché M.

Peptide-based vaccination-where do we stand? Curr Opin Allergy Clin Immunol. (2005) 5 537-43.

Larché M.

T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity. PLoS Medicine (2005) 2 e78. IF 13.75

Larché M.

The effect of Fel d 1-derived T cell peptides on upper and lower airway outcome measurements in cat-allergic subjects. Allergy (2005) 60 1269-1274. IF 5.33

Nair

The optimal starting dose of inhaled corticosteroids for asthma? Med Prakt 2005; 167 168: 153 7.

O'Byrne PM

 Budesonide/formoterol combination therapy as both maintence and reliever medication in asthma.  Am J Respir Crit Care Med 2005; 171:129-36

O'Byrne PM

Daily inhaled corticosteroids should be prescribed for mild persistent asthma.  Am J Respir Crit Care Med 2005; 172:410-2.

O'Byrne PM

Different Profiles in IFN-γ and IL-12 in Isolated Early and Dual Asthmatic Responders. J Allergy Clin Immunol 2005; 115:1004-9.

O'Byrne PM

Effects of low-dose ciclesonide on allergen-induced responses in subjects with mild allergic asthma.  J Allergy Clin Immunol 2005; 116: 285-9.

O'Byrne PM

Initiation, dose reduction, and duration of inhaled corticosteroid therapy. Immunol Allergy Clin North Am 2005; 25:511-21.

O'Byrne PM

Pharmacia Allergy Research Foundation and its award for young scientists in allergy research (Editorial).  Allergy: 2005; 60:269-70.

O'Byrne PM

Progenitor egress from the bone marrow after allergen challenge: role of SDF-1α and eotaxin.  J Allergy Clin Immunol 2005; 115:501-7

O'Byrne PM

Protection by budesonide and fluticasone on allergen-induced airway responses following discontinuation of therapy.  J Allergy Clin Immunol. 2005; 115:745-50.

O'Byrne PM

The links between allergen skin test sensitivity, airway hyperresponsiveness and airway responses to allergen.  Allergy: 2005; 60:56-9.

Sears MR

Asthma in remission: can relapse in early adulthood be predicted at age 18?  Chest 2005;127:845-50

Sears MR

Cost-effectiveness of formoterol and salbutamol as asthma reliever medication in Sweden and in Spain.  Int J Clin Pract 2005;59:62-68

Sears MR

Environmental inequality and circulatory disease mortality gradients. J Epidemiol Comm Health 2005; 59:481-7

Sears MR

Epidemiology of asthma.  In: Asthma Prevention.  Busse WW, Lemanske R, eds. Lung Biol Health Disease, 195, 2005.  Taylor & Francis, New York.

Sears MR

Past, present and future – b-adrenoceptor agonists in asthma management. Respir Med 2005; 99:152-170

Sears MR

Sex differences in factors associated with childhood- and adolescent-onset wheeze.  Am J Respir Crit Care Med 2005; 172:45-54.

Sears MR

Sex differences in the relation between body mass index and asthma and atopy in a birth cohort.  Am J Respir Crit Care Med 2005;171:440-445.

Sears MR

The September epidemic of asthma exacerbations in children: a search for etiology.  J Allergy Clin Immunol 2005;115:132-8.

Sehmi

Fish oil supplementation in pregnancy modifies neonatal progenitor s at birth in infants at risk of atopy. Pediatric Research 57:276-281. 2005

Sehmi

Hemopoietic mechanism in allergic rhinitis. Clinical Experimental Allergy 35:1-3; 2005

Sehmi

Increased eosinophil-lineage committed progenitor cells in the lung of allergen challenged mice.  J Allergy Clin Immunol 115:95-102. 2005

Sehmi

Role of SDF-1α and Eotaxin in modulating the egress of hemopoietic progenitors from the bone marrow in asthmatics following allergen challenge. Journal of Allergy and Clinical Immunology   115:501-507. 2005

Todd

Effect of combined montelukast and desloratidine on the early asthmatic response to inhaled allergen. J Allergy Clin Immunol 2005;116:768-772.

Todd

Importance of dosimeter calibration method on nebulizer output. Ann Allergy Asthma Immunol 2005;94:45-47.

Todd

Methacholine challenge: comparison of two methods. Chest 2005;127:839-844

Allen

Does laparoscopic fundoplication provide long-term control of gastroesophageal reflux related cough? Surgical Endoscopy and other Interventional Techniques    Volume: 18    Issue: 4    Pages: 633-637    Published: APR 2004

Cox

Cigarette smoke decreases pulmonary dendritic cells and impacts anti-viral immune responsiveness.  Am J Respir Cell Mol Biol. 2004; 30:202-211

Cox

Effect of freezing sputum samples on flow cytometric analysis of lymphocyte subsets.  Eur Respir J 2004; 24: 309-312

Cox

Extra-cellular matrix regulated human airway smooth muscle cell migration. Eur Resp J 2004;24:545-551

Cox

Radiofrequency ablation of airway smooth muscle for sustained treatment of asthma: rationale and preliminary investigations.  Eur Respir J 2004:24:659-663

Cox

Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs. J App Phys Jul 2004;10.1152

Dolovich

 Imaging Drug Delivery and Drug Responses in the Lung. Proc Am Thorac Soc 2004;1:339-337.

Dolovich

Canadian Standards Association (CSA) Standard CAN/CSA/Z264.1-02:2002 A New Voluntary Standard for Spacers and Holding Chambers Used With Pressurized Metered Dose Inhalers (pMDIs). Can Respir J 2004;11(7):489-495.

Dolovich

In My Opinion—Interview with the Expert. Pediatric Asthma, Allergy & Immunology 2004; 17(4): 292-300

Hargreave

An effective strategy for diagnosing occupational asthma: use of induced sputum.  Am J Crit Care Med 2004; 170: 845-70.

Hargreave

Effect of freezing sputum samples on flow cytometric analysis of lymphocyte subsets.  Eur Respir J 2004; 24:309-312.

Hargreave

Sputum CD34+IL-5Rα+Cells Increase after allergen evidence for in situ eosinophilopoiesis. Am J Respir Crit Care Med 2004; 169: 573-7

Inman

Concomitant airway expression of granulocyte macrophage colony stimulating factor and decorin, a natural inhibitor of transforming growth factor, breaks established inhalation tolerance. Eur J Immunol, 2004.

Inman

Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling. Am J Respir Crit Care Med:169(3):378 85, 2004.

Inman

Is interleukin-13 critical in maintaining airway hyerresponsiveness in allergen challenged mice? Am J Resp Crit Care Med, 2004.

Inman

Is there a place for anti-remodeling drugs in asthma which may not display immediate clinical efficacy? Eur Respir J. 24(1):1-2, 2004.

Inman

Kinetics of bone marrow eosinophilopoiesis and associated cytokines after allergen inhalation. Am J Respir Crit Care Med.169(5):565 72, 2004.

Inman

Reassessing the Th2 cytokine basis of asthma. Trends in Pharmacol. Sci (TIPS). 25(5):344-8, 2004

Inman

T cell mediated inflammation does not contribute to the maintenance of airway dysfunction in mice. J Appl Physiol. 2004.

Inman

TNF alpha is a critical negative regulator of type 1 immune activation during intracellular bacterial infection. J Clin Invest. Feb;113(3):401 13, 2004.

Inman

Type 2 cytokines in the pathogenesis of sustained airway dysfunction and airway remodeling in mice. Am.J.Resp.Crit.Care Med.169(7):860-6, 2004

Janssen

Augmentation of bovine airway smooth muscle responsiveness to carbachol, KCl and histamine by the isoprostane 8-iso PGE2.  American Journal of Physiology 287:L1035-41, 2004

Janssen

Enhanced myosin phosphatase and Ca2+-uptake mediate adrenergic relaxation of airway smooth muscle.  American Journal of Respiratory Cellular and Molecular Biology 30:548-554, 2004

Janssen

Extra-cellular matrix regulates human airway smooth muscle cell migration.  European Respiratory Journal 24:545-552, 2004

Janssen

KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase.  American Journal of Physiology 287: L852-858, 2004

Janssen

Mechanical and electrophysiological effects of isoprostanes on bronchial arterial smooth muscle.  Archives of Physiology and Biochemistry 111(4):337-339, 2004

Janssen

On the terminology for describing the length-force relationship and its changes in airway smooth muscle.  Journal of Applied Physiology 97:2029-34, 2004

Janssen

Pulmonary biology of isoprostanes.  Chemistry and Physics of Lipids 128:101-116, 2004

Janssen

The bronchodilators 8-iso PGE2 and PGE2 exert paradoxical effects on membrane K+ currents.  European Respiratory Journal 501:179-184, 2004

Janssen

Vascular relaxation response to hydrogen peroxide is impaired in hypertension.  British Journal of Pharmacology 142:143-149, 2004

Kolb

Bioterrorism and the Lung. Dtsch Med  Wochenschr 2004; 129: 93-96. (German)

Kolb

CTGF is crucial to induce a profibrotic environment in "fibrosis resistant" Balb/c mouse lungs. Am J Respir Cell Mol Biol 2004; 31: 510-516

Kolb

Smad3 null mice develop airspace enlargement and are resistant to TGF -mediated pulmonary fibrosis. J Immunol 2004; 173: 2099-210

Larché M.

 Cat allergen peptide immunotherapy reduces CD4+ T cell responses to cat allergen but does not alter suppression by CD4+CD25+ T cells: a double blind placebo controlled study. Allergy (2004) 59 1097-1101. IF 5.33

Larché M.

Allergen immunotherapy with cat allergen peptides. Springer Seminars in Immunopathology  D. Umetsu ed. (2004) 25: 391-399. IF 4.75

Larché M.

Induction of antigen-specific T cell regulation through peptide immunotherapy. In: Allergy Frontiers and Futures. Allergy & Clinical Immunology International. Bienenstock, Ring & Togias Eds. Hogrefe & Huber, Cambridge, MA, USA (2004) pp. 320-323

Larché M.

Investigating T cell activation and tolerance in vivo: peptide challenge in allergic asthmatics. Cytokine (2004) 28 49-54. IF 2.36

Larché M.

Late asthmatic reactions induced by inhalation of allergen-derived T cell peptides. Am J Respir Crit Care Med (2004) 169 20-26. IF 8.69

Larché M.

New approaches to immunotherapy:allergen-derived peptides. CPD Bulletin, Royal College of Physicians (2004) 3: 73-76

Larché M.

Novel approaches for immunotherapy for inhalant allergens. In: Lockey, Bukantz, Bousquet eds. Allergens and Allergen Immunotherapy. 3rd ed. New York: Marcel Dekker, (2004) pp641-661.

Larché M.

Regulatory T cells in allergic disease. J. Clin. Invest. (2004) 114 1389-1397. IF 14.2

Larché M.

The effects of T cell peptides in patients allergic to cats. Clin. Exp. All. Rev. (2004) 4: 1-6

McIvor RA

Comparative efficacies and tolerabilities of intravenous azithromycin plus ceftriaxone and intravenous levofloxacin with step-down oral therapy for hospitalized patients with moderate to severe community acquired pneumonia. Treat Respir Med 2004: 3 (5): 329-336

McIvor RA

Exclusion Spirometry: A bad idea. Can Respir J 2004: 3 (11): 186-187 Editorial

McIvor RA

Plasma D-Dimer for outcome assessment in patients with CAP. Not a replacement for PSI Chest  Oct 2004: 126 (4) : 1015-1016. Editorial

McIvor RA

The Canadian Optimal Therapy of COPD Trial: Design, Organization, and Patient Recruitment Can Respir J 2004: 11 (8) Nov/Dec: 581-585

Nair

Extracellular matrix regulates human airway smooth muscle cells migration. Eur Respir J 2004; 24: 545 51.

Nair

Leukotriene antagonists for asthma: are the long term benefits better than the short term gains? Med Prakt 2004:160:150 156.

Nair

Leukotriene receptor antagonists for allergic rhinosinusitis: a systematic overview and meta analysis. Am J Med 2004; 116:338 344.

Nair

Long acting beta agonists for asthma. Evid Based Med 2004; 9:139.

Nair

Role for cysteinyl leukotrienes in allergen induced change in circulating dendritic cell number in asthma. J Allergy Clin Immunol 2004; 114:73 9.

Nair

s doubling the dose of inhaled corticosteroids the best strategy to treat asthma exacerbations? Med Prakt 2004; 163: 124 5.

Nair

The effect of pranlukaston allergen induced bone marrow eosinophilopoiesis in subjects with asthma. Am J Respir Crit Care Med 2004; 169: 915-20

O'Byrne PM

 Different profiles of IL-10 production in circulating T-cells of atopic asthmatics from atopic non-asthmatics and healthy subjects.  Can Respir J 2004; 11:33-38

O'Byrne PM

A role for cysteinyl leukotrienes in allergen-induced change in circulating dendritic cell number in subjects with asthma.  J Allergy Clin Immunol 2004; 114:73-9.

O'Byrne PM

Adult asthma guidelines: update  Canadian Resp J: 2004; 11; 1-33.

O'Byrne PM

An economic evaluation of combination treatment with budesonide and formoterol in patients with mild-to-moderate persistent asthma.  Respir Med. 2004;98:1146-54.

O'Byrne PM

Extra-cellular matrix regulates migration of human airway smooth muscle cells.  Eur Respir J: 2004; 24:545-51.

O'Byrne PM

Increases in CD34+IL-5Rα+ cells in induced-sputum from atopic asthmatic subjects following allergen inhalation challenge: evidence for in situ eosinophilopoeisis.  Am J Respir Crit Care Med: 2004;169:573-577

O'Byrne PM

Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta- analysis.  Am J Med 2004; 116:338-44.

O'Byrne PM

Pharmacological interventions to reduce the risk of asthma exacerbations.  Proc Am Thorac Soc 2004; 1:105-108.

O'Byrne PM

Reassessing the Th2 cytokine basis of asthma.  Trends in Pharmacol. Sci.(TIPS): 2004; 25:244-248

O'Byrne PM

Relationship between quality of life and clinical status in asthma: a factor analysis.   Eur Respir J 2004; 23:287-91.

O'Byrne PM

The effect of Pranlukast, a leukotriene receptor antagonist, on allergen-induced airway eosinophilia and bone marrow eosinophil progenitors in asthmatic subjects.   Am J Respir Crit Care Med 2004;169: 915-20.

O'Byrne PM

The kinetics of eosinophilopoiesis and associated cytokines after allergen inhalation.  Am J Respir Crit Care Med: 2004; 169:565-72.

O'Byrne PM

Type 2 Cytokines in the Pathogenesis of Sustained Airway Dysfunction and Airway Remodeling in Mice.  Am J Respir Crit Care Med: 2004; 169:860-7

Sears MR

Canadian Adult Consensus Group of the Canadian Thoracic Society. Can Respir J. 2004;11:9A-18A, references 31A-33A

Sears MR

Doubling the dose of budesonide versus maintenance treatment in asthma exacerbations.  Thorax 2004;59:550-556

Sears MR

Geographic and gender variability in the prevalence of bronchial responsiveness in Canada.  Chest 2004;125:1657-1664

Sears MR

Relationship between socioeconomic status and asthma: a longitudinal cohort study.  Thorax 2004; 59 376-80

Sears MR

Response to “Breastfeeding, asthma and atopic disease: an epidemiologic review of the literature” by Oddy and Peat.  J Hum Lact 2004;20:148-50.

Sears MR

Traffic air pollution and mortality rate advancement periods. Am J Epidemiol 2004;160:173-177

Sehmi

Sputum CD34+IL-5Ralpha+ cells increase after allergen: evidence for in situ eosinophilopoeisis.  Am J Respir Crit Care Med 169:573-577. 2004

Sehmi

T-cell mediated inflammation is not required for sustained AHR that persists in mice following chronic allergen challenge Journal Appl. Physiol 97:2258-65. 2004

Sehmi

The effects of pranlukast, a cysteinyl leukotriene receptor antagonist, on allergen-induced airway eosinophilia and bone marrow eosinophil progenitors in asthmatic subjects Am J Respir Crit Care Med 169:915-20. 2004

Sehmi

The kinetics of bone marrow eosinopoiesis and associated cytokines after allergen inhalation. Am J Respir Crit Care Med 169:565-72. 2004

Todd

Dosimeter methacholine challenge: comparison of maximal and submaximal inhalations. J Allergy Clin Immunol 2004;114:517-519

Todd

Method of nebulizer calibration and methacholine airway hyperresponsiveness. J Allergy Clin Immunol 2004;114:1474-1475

Todd

Prolonged survival in Churg-Strauss syndrome. Ann Allergy Asthma Immunol 2004;92:92-93.

Allen

Does laparoscopic antireflux surgery prevent the occurrence of transient lower esophageal sphincter relaxtion?SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES    Volume: 17    Issue: 7    Pages: 1050-1054    Published: JUL 2003 

Cox

A method to preserve sputum for delayed examination.  Eur Respir J 2003; 22: 996-1000

Cox

The prevalence of vertebral fractures among patients with chronic obstructive pulmonary disease (COPD) in Canada.  Osteoporosis International, 2003; 14: 913-917

Dolovich

Clinical models to compare the safety and efficacy of inhaled corticosteroids in patients with asthma. Can Resp J. 2003 Jan-Feb;10 :27-34

Dolovich

Positron Emission Tomography and [18F]fluorodeoxyglucose: An Indicator of Lung Inflammation in Cystic Fibrosis?  ERJ 2003; 21:848-54

Dolovich

Pulmonary Drug Delivery Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications.   Br J Clin Pharmacol 2003;56:588-599.

Dolovich

Pulmonary Drug Delivery Part II: The role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications. Br J Clin Pharmacol 2003; 56:600-612.

Hargreave

A method to preserve sputum for delayed examination.  Eur Respir J 2003; 22:996-1000

Hargreave

Airway inflammation in COPD: physiological outcome measures and induced sputum.  Eur Respir J 2003; 21: (Suppl. 41); 19s – 28s

Hargreave

Clinical models to compare the safety and efficacy of inhaled corticosteroid in patients with asthma.  Can Resp J 2003; Jan-Feb; 10:27-38

Hargreave

Indirect airway challenges.  Eur Respir J 2003; 21: 1050-68

Inman

Do complex conditions require complex treatment?  Am.J.Resp.Crit.Care Med.15;167:6, 2003.

Inman

Morphornetric analysis of mouse airways after chronic allergen challenge. Lab.Invest. 83:1285-1291, 2003.

Janssen

Electrophysiological effects of erythromycin, but lack of mechanical effects, in airway smooth muscle.  European Journal of Pharmacology 475:93-97, 2003

Janssen

Mechanisms of hydrogen peroxide-induced biphasic response in rat mesenteric artery.  British Journal of Pharmacology 138:1085-1092, 2003

Janssen

Silk suture used for standard organ bath studies contracts upon exposure to Krebs buffer.  Journal of Pharmacological and Toxicological Methods 48:179-183, 2003

Janssen

Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle.  British Journal of Pharmacology 140:759-763, 2003

Janssen

Vasodilatory and membrane hyperpolarizing actions of 8-iso prostaglandin E2 in porcine coronary artery.  Journal of Pharmacology and Experimental Therapeutics 305:1054-1060, 2003

Kolb

A Re-evaluation of Fibrogenic Cytokines in Lung Fibrosis. Curr Pharm Des 2003;9:39-49

Kolb

Adenoviral gene transfer of connective tissue growth factor in the lung induces transient fibrosis. Am J Respir Crit Care Med 2003; 168:770-8.

Kolb

The role of cytokines and growth factors in fibroproliferative lung disease. Pneumologie, 2003, 57: 91-97. (German)

Labiris

Pulmonary Drug Delivery. Part I: Physiological Factors affecting Therapeutic Effectiveness of Aerosolized Medications. British Journal of Clinical Pharmacology 2003 56(6):588-599

Labiris

Pulmonary Drug Delivery. Part II: The Role of Inhalatant Delivery Devices and Drug Formulations in Therapeutic Effectiveness of Aerosolized Medications. British Journal of Clinical Pharmacology 2003 56(6):600-612.

Labiris

Uptake of 18Fluorodeoxyglucose in the Cystic Fibrosis Lung: A Measure of Lung Inflammation? European Respiratory Journal 2003 21:848-854.

McIvor RA

Adjustable maintenance dosing with budesonide/formoterol reduces asthma exacerbations compared with traditional fixed dosing: a 5-month multicenter Canadian study. Can Respir J 2003: 10 (8) Nov/Dec: 427-434

McIvor RA

Antimicrobials in acute exacerbations of chronic obstructive pulmonary disease -An analysis of the time to next exacerbation before and after implementation of standing orders Can J Infectious Dis  2003: 14 (5 ) Sept/Oct : 254 – 259

McIvor RA

Inhaled corticosteroids should not be described to all COPD patients Can Respir J 2003:10 (3); 148-149.

McIvor RA

Utilization of Inhaled Corticosteroids in Hospitalized Patients with COPD, A Quality Review and Update on the Current Literature Can J Hosp Pharmacy April 2003: 56 (2); 142-154

O'Byrne PM

 Airway hyperresponsiveness.  Chest: 2003; 123:411S-416S.

O'Byrne PM

Allergen-induced fluctuation in CCR3 expression on bone marrow CD34+ cells from asthmatic subjects: significance for mobilization of hemopoietic progenitor cells in allergic inflammation.  Immunology: 2003; 109:536-546.

O'Byrne PM

Clinical models to compare the safety and efficacy of inhaled corticosteroids in patients with asthma.  Can Resp J 2003: Jan-Feb; 10:27-34.

O'Byrne PM

Early intervention with budesonide in mild persistent asthma.  Lancet 2003; 361:1071-6.

O'Byrne PM

Inhaled corticosteroids for asthma: common clinical quandries.  J Asthma 2003; 40:107-18.

O'Byrne PM

Morphometric analysis of mouse airways after chronic allergen challenge.  Lab Invest. 2003; 83: 1285-91.

O'Byrne PM

The effects of an anti-CD11a monoclonal antibody, Efalizumab, on allergen-induced airway responses and airway inflammation in atopic asthma.  J Allergy Clin Immunol 2003; 112:331-8.

Sears MR

 Breastfeeding and asthma: appraising the controversy - a rebuttal.  Pediatr Pulmonol 2003;36:366-368

Sears MR

 Formoterol as relief medication in asthma: a worldwide safety and effectiveness trial. Eur Respir J 2003;22:787-794

Sears MR

Adjustable maintenance dosing with budesonide/formoterol reduces asthma exacerbations compared with traditional fixed dosing: A five-month multicentre Canadian study.  Can Respir J 2003;10:427-434.

Sears MR

Canadian Network for Asthma Care:  Canadian Thoracic Society.  Canadian Pediatric Asthma Consensus guidelines, 2003 (updated to December 2004).  Cdn Med A J 2005;13:S12-S14.

Sears MR

Childhood asthma followed to adulthood: a longitudinal population- based cohort study.  N Engl J Med. 2003 ;3449:1414-22.

Sears MR

Environmental justice: a cohort study of income, air pollution and mortality.  Can Med Assn J. 2003;169:397-402.

Sears MR

Inhaled corticosteroids for asthma: common clinical quandaries. J Asthma  2003;40:107-118

Sears MR

Risk factors for development of asthma.  Eur Respir Mon. 2003: 23:51-73

Sehmi

Allergen-induced fluctuations in CC chemokine receptor 3 expression on bone marrow CD34+ cells from asthmatic subjects: significance for mobilization of hemopoietic progenitor cells in allergic inflammation. Immunology 109(4):536-46 2003

Sehmi

Anti-IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturation and decreased eosinophil progenitors in the bronchial mucosa of atopic asthmatics.  J Allergy Crit Care Med 111(4):714-9; 2003